Article

Quantitative model suggests both intrinsic and contextual features contribute to the transcript coding ability determination in cells

2021-11-02

Abstract excerpt

Gene transcription and protein translation are two key steps of the “ central dogma ”. It is still a major challenge to quantitatively deconvolute factors contributing to the coding ability of transcripts in mammals. Here, we propose Ribosome Calculator (RiboCalc) for quantitatively modeling the coding ability of RNAs in human genome. In addition to effectively predicting the experimentally confirmed coding abund...

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Identifiers and source

Literature Corpus work: 3163dd76-2c2d-5b62-a9ac-81533ceba98b
DOI: 10.1101/2021.10.30.466534

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