Article

Defective RNA Polymerase III is negatively regulated by the SUMO-Ubiquitin-Cdc48 Pathway

2018-02-04

Abstract excerpt

<h4>ABSTRACT</h4> Transcription by RNA polymerase III (Pol III) is an essential cellular process, and mutations in Pol III can cause neurodegenerative disease in humans. However, in contrast to Pol II transcription, which has been extensively studied, the knowledge of how Pol III is regulated is very limited. We report here that in budding yeast, Saccharomyces cerevisiae , Pol III is negatively regulated by the...

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Literature Corpus work: 31507082-b4fa-5f67-babb-27e51b93eacb
DOI: 10.1101/259846

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