Article

The combination of differential expression and differential network connectivity analyses identifies RNA splicing and processing as common pathways altered with age across human tissues

2023-05-28

Abstract excerpt

<h4>ABSTRACT</h4> Transcriptomic changes occur with age, but the extent of their similarities across tissues is not clear. Previous studies have identified no similarity in age-modulated genes in different tissues. In this study, we sought to identify transcriptional changes with age across tissues using differential network analysis, with the premise that differential expression analysis alone is not capable of...

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Literature Corpus work: 3136019d-4dd6-5cbd-83ce-d102783dbf47
DOI: 10.1101/2023.05.26.542445

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