Article

SLFN-generated 3′-truncated tRNA <sup>Leu</sup> or tRNA <sup>Ser</sup> together with tRNase Z <sup>L</sup> works as a sequence-specific RNA cutter

2026-04-13

Abstract excerpt

A complex of the 3′-truncated tRNA Arg that lacks 9 nt and tRNase Z L works as a GCCC-recognizing RNA cutter. It recognizes an RNA substrate via four Watson-Crick-Franklin base-pairings with the 3′-truncated tRNA Arg . Human SLFN11 and SLFN13 can generate 3′-truncated tRNA Leu that lacks 10 nt and 3′-truncated tRNA Ser that lacks 11 nt, respectively, from their corresponding mature tRNAs. Here, we investigate...

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Literature Corpus work: 31259fc9-c110-5f59-97ad-679f0ce8e5a2
DOI: 10.64898/2026.04.12.718003

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SLFN-generated 3′-truncated tRNA <sup>Leu</sup> or tRNA <sup>Ser</sup> together with tRNase Z <sup>L</sup> works as a sequence-specific RNA cutterDOI 10.64898/2026.04.12.718003Read

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