Article
The flexible arm of tRNase Z is not essential for pre-tRNA binding but affects cleavage site selection.
Journal of molecular biology - 29 Aug 2008
Minagawa Asako, Ishii Ryohei, Takaku Hiroaki, Yokoyama Shigeyuki, Nashimoto Masayuki
Abstract excerpt
tRNase Z is an enzyme responsible for removing a 3' trailer from pre-tRNA. Although most tRNase Zs cleave pre-tRNAs immediately after the discriminator nucleotide with the exception of Thermotoga maritima tRNase Z, which cleaves after the (74)CCA(76) sequence, our knowledge was limited about how...
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