Article
ACA-specific RNA sequence recognition is acquired via the loop 2 region of MazF mRNA interferase.
Proteins - 1 May 2013
Park Jung-Ho, Yoshizumi Satoshi, Yamaguchi Yoshihiro, Wu Kuen-Phon, Inouye Masayori
Abstract excerpt
MazF is an mRNA interferase that cleaves mRNAs at a specific RNA sequence. MazF from E. coli (MazF-ec) cleaves RNA at A^CA. To date, a large number of MazF homologs that cleave RNA at specific three- to seven-base sequences have been identified from bacteria to archaea. MazF-ec forms a dimer, in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
