Article

Reversing increased neuronal nitric oxide synthase in Alzheimer’s disease prevents aberrant glutamatergic calcium responses

2022-11-29

Abstract excerpt

<title>Abstract</title> <p>Background Nitrosative stress is a feature of Alzheimer’s disease, however the underlying mechanisms driving nitrosative stress and the impact of nitric oxide on neuronal function in Alzheimer’s disease is still largely unknown. Methods We analysed neuronal nitric oxide synthase (nNOS) protein levels in post mortem tissue and induced pluripotent stem cell (iPSC) derived neurons from A...

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Literature Corpus work: 30eba8ff-45dd-5838-aae0-c8b10ff3ba0a
DOI: 10.21203/rs.3.rs-2257266/v1

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