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Article

Nitration of tyrosine 10 critically enhances amyloid β aggregation and plaque formation.

Neuron - 8 Sept 2011

Kummer Markus P, Hermes Michael, Delekarte Andrea, Hammerschmidt Thea, Kumar Sathish, Terwel Dick, Walter Jochen, Pape Hans-Christian, König Simone, Roeber Sigrun, Jessen Frank, Klockgether Thomas, Korte Martin, Heneka Michael T

Abstract excerpt

Part of the inflammatory response in Alzheimer's disease (AD) is the upregulation of the inducible nitric oxide synthase (NOS2) resulting in increased NO production. NO contributes to cell signaling by inducing posttranslational protein modifications. Under pathological conditions there is a shif...

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Source

Identifiers

PMID: 21903077
DOI: 10.1016/j.neuron.2011.07.001

Genes

NOS2
APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21903077-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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