Article

Macrophage-derived CCL24 promotes fibrosis and worsens cardiac dysfunction during heart failure

2024-07-16

Abstract excerpt

<h4>ABSTRACT</h4> Inflammation is a significant risk factor and contributes to cardiovascular disease by driving both adaptive and maladaptive processes. Macrophages are the most abundant immune cells in the heart and play an important role in the remodeling of cardiac tissue. We have previously shown an overall protective function of resident cardiac macrophages after pressure-overloaded injury. However, a subpo...

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Literature Corpus work: 30e1f48d-c41f-5b17-a72c-15b553594216
DOI: 10.1101/2024.07.12.603277

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