Article

Effects of Pesticide Exposure on Neuroinflammation and Microglial Gene Expression: Relevance to Mechanisms of Alzheimer’s Disease Risk

2025-02-20

Abstract excerpt

<h4>Background</h4> Alzheimer’s disease (AD) is characterized by the presence of amyloid-β plaques, neurofibrillary tangles, and neuroinflammation. Previously, we reported serum levels of dichlorodiphenyldichloroethylene (DDE), the primary metabolite of the pesticide dichlorodiphenyltrichloroethane (DDT), were significantly higher in AD patients compared to age-matched controls and that DDT exposure worsened AD p...

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Literature Corpus work: c16daedf-6841-5d44-b200-ae751ac59cc4
DOI: 10.1101/2025.02.14.638293

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