Article

Characterization of a flexible AAV-DTR/DT mouse model of acute epithelial lung injury

2021-06-18

Abstract excerpt

<h4>Background & aim</h4> Recurring epithelial injury and aberrant repair are considered as a major driver of idiopathic pulmonary fibrosis (IPF) leading to chronic inflammation, fibroblast activation and ultimately to scarring and stiffening of the lung. As decline of lung function is the first reported symptom by IPF patients and occurs once fibrosis is firmly established, animal models are required to study ea...

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Literature Corpus work: 30ae4e6a-57f0-5ce2-b351-5d9b3cb913f5
DOI: 10.1101/2021.06.18.445859

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