Article
What Has a Century of Quantitative Genetics Taught Us About Nature's Genetic Tool Kit?
Annual review of genetics - 23 Nov 2020
Jakobson Christopher M, Jarosz Daniel F
Abstract excerpt
The complexity of heredity has been appreciated for decades: Many traits are controlled not by a single genetic locus but instead by polymorphisms throughout the genome. The importance of complex traits in biology and medicine has motivated diverse approaches to understanding their detailed genetic bases. Here, we focus on recent systematic studies, many in budding yeast, which have revealed that large numbers of...
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