Article

Visualizing Molecules of Functional <i>Human</i> Profilin

2021-09-02

Abstract excerpt

Profilin-1 (PFN1) is a cytoskeletal protein that regulates the dynamics of actin and microtubule assembly. Thus, PFN1 is essential for the normal division, motility, and morphology of cells. Unfortunately, conventional fusion and direct labeling strategies compromise different facets of PFN1 function. As a consequence, the only methods used to determine known PFN1 functions have been indirect and often deduced in...

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Literature Corpus work: 3020ee7c-f879-5ea5-9a79-fd8b8cc4c066
DOI: 10.1101/2021.09.01.458557

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