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Enrichment of short mutant cell-free DNA fragments enhanced detection of pancreatic cancer

2018-12-04

Abstract excerpt

Analysis of cell-free DNA (cfDNA) is promising for broad applications in clinical settings, but with significant bias towards late-stage cancers. Although recent studies have discussed the diverse and degraded nature of cfDNA molecules, little is known about its impact on the practice of cfDNA analysis. Here we reported a new targeted sequencing by combining single-strand library preparation and target capture (SL...

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Literature Corpus work
2fcc07c4-5f7e-55bb-be59-181fc18c0427
DOI
10.1101/482745
Open publication

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Enrichment of short mutant cell-free DNA fragments enhanced detection of pancreatic cancerDOI 10.1101/482745
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