Article
Cell free DNA in patients with pancreatic adenocarcinoma: clinicopathologic correlations.
Scientific reports - 8 Jul 2024
Theparee Talent, Akroush Michael, Sabatini Linda M, Wang Vivien, Mangold Kathy A, Joseph Nora, Stocker Susan Jane, Freedman Alexa, Helseth Donald L, Talamonti Mark S, Kaul Karen L
Abstract excerpt
Detection of circulating tumor DNA (ctDNA) from plasma cell free DNA (cfDNA) has shown promise for diagnosis, therapeutic targeting, and prognosis. This study explores ctDNA detection by next generation sequencing (NGS) and associated clinicopathologic factors in patients with pancreatic adenocarcinoma (PDAC). Patients undergoing surgical exploration or resection of pancreatic lesions were enrolled with informed...
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