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NGS-Based Tumor-Informed Analysis of Circulating Tumor DNA.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2023

Nordentoft Iver, Birkenkamp-Demtröder Karin, Dyrskjøt Lars

Abstract excerpt

Accurate circulating tumor DNA (ctDNA) detection has an immense biomarker potential in all phases of the cancer disease course. Presence of ctDNA in the blood has been shown to have prognostic value in various cancer types as it may reflect the actual tumor burden. There are two main methods to consider, a tumor-informed and a tumor-agnostic analysis of ctDNA. Both techniques exploit the short half-life of...

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PMID: 37410235
DOI: 10.1007/978-1-0716-3291-8_11

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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