Article

Extracellular vesicles from a novel chordoma cell line, ARF-8, promote tumorigenic microenvironmental changes when incubated with the parental cells and with human osteoblasts

2024-10-06

Abstract excerpt

<h4>ABSTRACT</h4> Chordomas are rare, generally slow-growing spinal tumors that nonetheless exhibit progressive characteristics over time, leading to malignant phenotypes and high recurrence rates, despite maximal therapeutic interventions. The tumors are notoriously resistant to therapies and are often in locations that make gross total resections difficult. Here, we describe a new chordoma cell line (ARF-8) der...

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Literature Corpus work: 2f9cb0b3-411a-56cb-8846-03c403e1d5e0
DOI: 10.1101/2024.10.06.616873

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