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Article

Establishment and detailed functional and molecular genetic characterisation of a novel sacral chordoma cell line, MUG-Chor1.

International journal of oncology - 1 Feb 2012

Rinner Beate, Froehlich Elke Verena, Buerger Karin, Knausz Heike, Lohberger Birgit, Scheipl Susanne, Fischer Carina, Leithner Andreas, Guelly Christian, Trajanoski Slave, Szuhai Karoly, Liegl Bernadette

Abstract excerpt

Chordomas are rare, low to intermediate grade malignant bone tumors of the axial skeleton. Current treatment options are limited to surgical procedures, as chordomas are largely resistant to conventional radiation and chemotherapy. Cell lines are valuable tools for exploring molecular mechan-isms involved in tumorigenesis and they have a fundamental impact on the development of new anticancer agents. To date,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22002331
DOI: 10.3892/ijo.2011.1235

Genes

PDCD4
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Establishment and detailed functional and molecular genetic characterisation of a novel sacral chordoma cell line, MUG-Chor1.PMID 22002331Read ↗

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