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Article

Extracellular vesicle bioactivity and potential clinical utility is determined by mesenchymal stromal cell clonal subtype

2024-09-05

Abstract excerpt

Mesenchymal stromal cells (MSCs) are a promising source of therapeutic extracellular vesicles (EVs), however it is not clear how heterogeneity within a non-clonal MSC population will affect the collective EV pool. Here we used immortalised clonal MSC lines, termed Y201 and Y202, to examine how MSC phenotype influences EV character and function. Although morphologically similar, Y201 EVs were more abundant in EV bi...

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Identifiers and source

Literature Corpus work
653a4120-3065-5186-adfc-943f79b04d83
DOI
10.1101/2024.09.05.609844
Open publication

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Extracellular vesicle bioactivity and potential clinical utility is determined by mesenchymal stromal cell clonal subtypeDOI 10.1101/2024.09.05.609844
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