Article

Alterations in neural stem cell quiescence and activation in the 3xTG-AD model of Alzheimer’s Disease

2022-06-09

Abstract excerpt

Alzheimer’s Disease (AD) is the most common form of dementia with progressive cognitive deficits and mood disorders (Knopman et al., 2021). Recent studies have associated AD pathology with the impairment of adult neurogenesis, as indicated by impaired neural stem cell (NSCs) homeostasis (Bond et al., 2015). Recent work has further associated AD progression with a decline in the number and maturation of adult-born...

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Literature Corpus work: c7c81c95-efe1-5e9d-8f72-1ab2ba56bde6
DOI: 10.1101/2022.06.08.495344

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