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IGHV1-69 BCRs with virus-neutralizing mutations show lymphoma-like transcriptomes in patients with chronic HCV infection

2023-03-29

Abstract excerpt

<title>Abstract</title> <p>Chronic hepatitis C virus (HCV) infection leads to a complex interplay with adaptive immune cells that may result in cryoglobulinemia or lymphoma. Although direct-acting antiviral (DAA) therapy has decreased the incidence of severe liver damage, its effect on extrahepatic HCV manifestations such as B cell dyscrasias is still unclear. Here, we used immunosequencing to analyze HCV imprint...

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Literature Corpus work
2f273e8e-9a46-5d3e-9a4c-cf1efe9877a4
DOI
10.21203/rs.3.rs-2719495/v1
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IGHV1-69 BCRs with virus-neutralizing mutations show lymphoma-like transcriptomes in patients with chronic HCV infectionDOI 10.21203/rs.3.rs-2719495/v1
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