Article

A novel recombination protein C12ORF40/REDIC1 is required for meiotic crossover formation

2022-08-24

Abstract excerpt

<title>Abstract</title> <p>During meiosis, at least one crossover must occur in each chromosome pair to ensure their accurate segregation. However, the mechanism of crossover formation is poorly understood. Here, we report a previously uncharacterized recombination protein, C12ORF40/REDIC1, essential for meiotic crossover formation. A homozygous frameshift mutation in C12orf40 was identified in two genetically un...

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Literature Corpus work: 2f0d365e-d6f8-5a8a-8c35-12762b3c30b2
DOI: 10.21203/rs.3.rs-1971629/v1

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