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Article

C14ORF39/SIX6OS1 is a constituent of the synaptonemal complex and is essential for mouse fertility.

Nature communications - 31 Oct 2016

Gómez-H Laura, Felipe-Medina Natalia, Sánchez-Martín Manuel, Davies Owen R, Ramos Isabel, García-Tuñón Ignacio, de Rooij Dirk G, Dereli Ihsan, Tóth Attila, Barbero José Luis, Benavente Ricardo, Llano Elena, Pendas Alberto M

Abstract excerpt

Meiotic recombination generates crossovers between homologous chromosomes that are essential for genome haploidization. The synaptonemal complex is a 'zipper'-like protein assembly that synapses homologue pairs together and provides the structural framework for processing recombination sites into crossovers. Humans show individual differences in the number of crossovers generated across the genome. Recently, an...

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Share to Chromosomal Proteins, Non-Histone
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27796301
DOI: 10.1038/ncomms13298
PMCID: PMC5095591

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C14ORF39/SIX6OS1 is a constituent of the synaptonemal complex and is essential for mouse fertility.PMID 27796301Read ↗

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