Article

Compound Heterozygous REC114 Variants in Dizygotic Twins Causes Meiotic Arrest and Non-Obstructive Azoospermia

2025-07-22

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> : Meiosis is essential for gametogenesis and the preservation of fertility. Central to this process is meiotic recombination, a mechanism that ensures accurate chromosome segregation and drives genetic diversity. Non-obstructive azoospermia (NOA), a severe form of male infertility, often results from meiotic arrest. Although monogenic mutations in genes critic...

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Literature Corpus work: bc3b1fb8-7c48-59a4-9307-4532e17eae21
DOI: 10.21203/rs.3.rs-7093595/v1

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