Article

A local tumor microenvironment acquired super-enhancer induces an oncogenic driver for efficient growth under oxidative conditions in colorectal carcinoma

2021-08-24

Abstract excerpt

<title>Abstract</title> <p>Tumors exhibit widespread enhancer landscape reprogramming compared to normal tissue. The etiology is believed to be largely cell-intrinsic in non-hormonal cancers, attributed to such genomic alterations as focal amplification of non-coding regions, aberrant activation of transcription factors, and non-coding mutations creating de novo transcription factor binding sites. Here, using fre...

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Literature Corpus work: 2ef55c75-4f3b-5332-8bcb-6f32422b2368
DOI: 10.21203/rs.3.rs-799320/v1

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