Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

T cell receptor (TCR) signaling in health and disease

13 Dec 2021

Abstract excerpt

Interaction of the T cell receptor (TCR) with an MHC-antigenic peptide complex results in changes at the molecular and cellular levels in T cells. The outside environmental cues are translated into various signal transduction pathways within the cell, which mediate the activation of various genes with the help of specific transcription factors. These signaling networks propagate with the help of various effector...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to Immune Cell Function and Interaction
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34897277
DOI: 10.1038/s41392-021-00823-w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

T cell receptor (TCR) signaling in health and diseasePMID 34897277Read ↗

The T-cell-receptor signaling networkSemantic proximity Read ↗

Molecular and genetic insights into T-cell antigen receptor signaling.Semantic proximity Read ↗

Molecular insights into T cell development, activation and signal transduction (Review)Semantic proximity Read ↗

The Role of T Cell Receptor Signaling in the Development of Type 1 DiabetesSemantic proximity Read ↗

The dynamics of T cell receptor signaling: complex orchestration and the key roles of tempo and cooperation.Semantic proximity Read ↗

T cell antigen-receptor signal transductionSemantic proximity Read ↗

Regulation of T-Cell Signaling by Post-Translational Modifications in Autoimmune DiseaseSemantic proximity Read ↗

The Dual Role of TAM Receptors in Autoimmune Diseases and Cancer: An OverviewSemantic proximity Read ↗

ZAP-70 in Signaling, Biology, and DiseaseSemantic proximity Read ↗

The Emerging and Diverse Roles of Src‐Like Adaptor Proteins in Health and DiseaseSemantic proximity Read ↗

Control of T lymphocyte fate decisions by PI3K signalingSemantic proximity Read ↗

The human T cell receptor in health and disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.