Article

DNA Nanotechnology-Empowered Fluorescence Imaging of APE1 Activity

2023-06-30

Abstract excerpt

Apurinic/apyrimidinic endonuclease 1 (APE1), also known as redox factor-1 (Ref-1), is a multifunctional protein which is widely existing in living organisms. It can specifically recognize and cleave the DNA in apurinic/apyrimidinic (AP) site in the base excision repair (BER) pathway, as well as regulate the expression of genes to activate some transcription factors. The abnormal ex-pression and disruptions in the...

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Literature Corpus work: 2e9fc16f-da51-5362-92d8-2dc80e5b924e
DOI: 10.20944/preprints202306.2208.v1

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