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Article

Invader assay-induced catalytic assembly of multi-DNAzyme junctions for sensitive detection of single nucleotide polymorphisms.

Analytica chimica acta - 1 Sept 2022

Li Xiaolong, Liao Lei, Jiang Bingying, Yuan Ruo, Xiang Yun

Abstract excerpt

Single nucleotide polymorphisms (SNPs) are main causes of differences in human phenotypes and drug resistance, especially the development of genetic diseases. Monitoring SNPs is of significant benefit to drug design and disease diagnosis. In this work, on the basis of tripartite DNAzyme junction formation induced by flap endonuclease 1 (FEN1) invader assay-triggered catalytic hairpin assembly (CHA), we describe...

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PMID: 35998991
DOI: 10.1016/j.aca.2022.340225

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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