Article
Research in a time of enteroids and organoids: how the human gut model has transformed the study of enteric bacterial pathogens
14 Aug 2020
Abstract excerpt
Enteric bacterial pathogens cause significant morbidity and mortality globally. Studies in tissue culture and animal models shaped our initial understanding of these host–pathogen interactions. However, intrinsic shortcomings in these models limit their application, especially in translational applications like drug screening and vaccine development. Human intestinal enteroid and organoid models overcome some...
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