Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Versatile Human Intestinal Organoid-Derived Epithelial Monolayer Model for the Study of Enteric Pathogens

13 Jun 2021

Abstract excerpt

While traditional laboratory techniques and animal models have provided valuable knowledge in discerning virulence mechanisms of enteric pathogens, the complexity of the human gastrointestinal tract has hindered our understanding of physiologically relevant, human-specific interactions and, thus, has significantly delayed successful vaccine development. The human intestinal organoid-derived epithelial monolayer...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteriophages and microbial interactions
Share to Cancer Cells and Metastasis
Share to Viral gastroenteritis research and epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34106568
DOI: 10.1128/spectrum.00003-21

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Versatile Human Intestinal Organoid-Derived Epithelial Monolayer Model for the Study of Enteric PathogensPMID 34106568Read ↗

Research in a time of enteroids and organoids: how the human gut model has transformed the study of enteric bacterial pathogensSemantic proximity Read ↗

Gastrointestinal organoids in the study of viral infectionsSemantic proximity Read ↗

Human intestinal organoids as models to study enteric bacteria and virusesSemantic proximity Read ↗

Put Some Guts into It: Intestinal Organoid Models to Study Viral InfectionSemantic proximity Read ↗

Organoids to Dissect Gastrointestinal Virus–Host Interactions: What Have We Learned?Semantic proximity Read ↗

Stem Cell-Derived Models of Viral Infections in the Gastrointestinal TractSemantic proximity Read ↗

A Human 2D Primary Organoid-Derived Epithelial Monolayer Model to Study Host-Pathogen Interaction in the Small IntestineSemantic proximity Read ↗

Human Intestinal Organoids Recapitulate Enteric Infections of Enterovirus and CoronavirusSemantic proximity Read ↗

Spheres of Influence: Insights into Salmonella Pathogenesis from Intestinal OrganoidsSemantic proximity Read ↗

Salmonella enterica serovar Typhimurium SPI-1 and SPI-2 shape the transcriptional landscape of epithelial cells in a human intestinal organoid model systemSemantic proximity Read ↗

An Advanced Human Intestinal Coculture Model Reveals Compartmentalized Host and Pathogen Strategies during Salmonella InfectionSemantic proximity Read ↗

Insights into Human Norovirus Cultivation in Human Intestinal EnteroidsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.