Article

<i>LTA4H</i>association with montelukast response in early and late-onset asthma

2020-10-06

Abstract excerpt

<h4>ABSTRACT</h4> Leukotrienes play a central pathophysiological role in both pediatric and adult asthma. However, 35% to 78% of asthmatics do not respond to leukotriene inhibitors. To test the role of the LTA4H regulatory variant rs2660845 and age of asthma onset in response to montelukast in ethnically diverse populations. We identified and genotyped 3,594 asthma patients treated with montelukast (2,514 late-ons...

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Literature Corpus work: 2e7184c4-e322-591f-81fd-5091e1107916
DOI: 10.1101/2020.10.05.20206847

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