Article

Rare variants in PLA2G7 are associated with the age of onset and disease burden of asthma

2023-06-29

Abstract excerpt

Understanding of the contributions of rare genetic variants in asthma is limited. In this study, we investigated this contribution in 121 asthma-associated genes to the age of onset and disease burden using targeted next-generation sequencing in 576 cases of asthma. The Sequence Kernel Association Test (SKAT) was used for cumulative rare variant association analysis, with asthma onset as the outcome. The median ag...

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Literature Corpus work: 7631e945-3da1-55e8-bada-3ac84c50d1e6
DOI: 10.21203/rs.3.rs-3014358/v1

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