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Article

Influence of leukotriene pathway polymorphisms on response to montelukast in asthma.

American journal of respiratory and critical care medicine - 15 Feb 2006

Lima John J, Zhang Shu, Grant Audrey, Shao Lianhe, Tantisira Kelan G, Allayee Hooman, Wang Jianwei, Sylvester James, Holbrook Janet, Wise Robert, Weiss Scott T, Barnes Kathleen

Abstract excerpt

RATIONALE: Interpatient variability in montelukast response may be related to variation in leukotriene pathway candidate genes. OBJECTIVE: To determine associations between polymorphisms in leukotriene pathway candidate genes with outcomes in patients with asthma receiving montelukast for 6 mo who participated in a clinical trial. METHODS: Polymorphisms were typed using Sequenom matrix-assisted laser...

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Source

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Identifiers

PMID: 16293801
DOI: 10.1164/rccm.200509-1412OC
PMCID: PMC2662939

Genes

ALOX5
FEV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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