Article
Evaluating the Evaluation of Cancer Driver Genes
2016-06-23
Abstract excerpt
Sequencing has identified millions of somatic mutations in human cancers, but distinguishing cancer driver genes remains a major challenge. Numerous methods have been developed to identify driver genes, but evaluation of the performance of these methods is hindered by the lack of a gold standard, i.e., bona fide driver gene mutations. Here, we establish an evaluation framework that can be applied when a gold stand...
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Identifiers and source
- Literature Corpus work
- 2e15cd4c-79a6-5a1e-aaee-3c34eddcf511
- DOI
- 10.1101/060426