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African swine fever virus MGF505-3R inhibits cGAS-STING-mediated IFN-β pathway activation by degrading TBK1

2022-06-20

Abstract excerpt

Abstract African swine fever virus (ASFV) is an important pathogen causing acute infectious disease in domestic pigs and wild boars that seriously endangers the global swine industry. As ASFV is structurally complex and encodes a large number of functional proteins, no effective vaccine has been developed to date. Thus, dissecting the mechanisms of immune escape induced by ASFV proteins is crucial. A previous stud...

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Literature Corpus work
2e155946-c18f-51fb-a4e5-8405726cb249
DOI
10.1186/s44149-022-00046-8
Open publication

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