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African swine fever virus pB475L evades host antiviral innate immunity via targeting STAT2 to inhibit IFN-I signaling

14 Jun 2024

Abstract excerpt

African swine fever virus (ASFV) causes severe disease in domestic pigs and wild boars, seriously threatening the development of the global pig industry. Type I interferon (IFN-I) is an important component of innate immunity, inducing the transcription and expression of antiviral cytokines by activating Janus-activated kinase–signal transducer and activator of transcription (STAT). However, the underlying...

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PMID: 38879005
DOI: 10.1016/j.jbc.2024.107472

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