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African swine fever virus MGF360-11L negatively regulates cGAS-STING-mediated inhibition of type I interferon production

24 Jan 2022

Abstract excerpt

The type I interferon (IFN-I) signaling pathway is an important part of the innate immune response and plays a vital role in controlling and eliminating pathogens. African swine fever virus (ASFV) encodes various proteins to evade the host's natural immunity. However, the molecular mechanism by which the ASFV-encoded proteins inhibit interferon production remains poorly understood. In the present study, ASFV...

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PMID: 35073979
DOI: 10.1186/s13567-022-01025-0

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