Article

Transcriptional profiling reveals running promotes cerebrovascular remodeling in young but not aged mice

2019-03-11

Abstract excerpt

<h4>Background</h4> The incidence of dementia and cognitive decline is increasing with no therapy or cure. One of the reasons treatment remains elusive is because there are various pathologies that contribute to age-related cognitive decline. Specifically, with Alzheimer’s disease, targeting to reduce amyloid beta plaques and phosphorylated tau aggregates in clinical trials has not yielded results to slow symptom...

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Literature Corpus work: 2e13fdd6-40c5-5782-8cd2-9c6929cc3167
DOI: 10.1101/574673

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