Article

Splenic MARCO <sup>+</sup> marginal zone macrophages regulate rapid production of MCP-1 and KC but are dispensable for alloantibody generation in response to stored RBCs in a murine model

2025-02-15

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> Alloimmunization to transfused red blood cells (RBCs) remains a significant clinical problem. However, the cells that initiate immune responses to transfused RBCs remain incompletely characterized. Recently published work has identified splenic marginal zone B (MZB) cells as being critically required for the production of anti-RBC alloantibodies in response to RBCs. In infec...

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Literature Corpus work: 2df70806-efa4-5f34-91b7-5f9a7f2729c5
DOI: 10.1101/2025.02.11.637644

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