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Article

Resolving Salmonella infection reveals dynamic and persisting changes in murine bone marrow progenitor cell phenotype and function.

European journal of immunology - 1 Aug 2014

Ross Ewan A, Flores-Langarica Adriana, Bobat Saeeda, Coughlan Ruth E, Marshall Jennifer L, Hitchcock Jessica R, Cook Charlotte N, Carvalho-Gaspar Manuela M, Mitchell Andrea M, Clarke Mary, Garcia Paloma, Cobbold Mark, Mitchell Tim J, Henderson Ian R, Jones Nick D, Anderson Graham, Buckley Christopher D, Cunningham Adam F

Abstract excerpt

The generation of immune cells from BM precursors is a carefully regulated process. This is essential to limit the potential for oncogenesis and autoimmunity yet protect against infection. How infection modulates this is unclear. Salmonella can colonize systemic sites including the BM and spleen. This resolving infection has multiple IFN-γ-mediated acute and chronic effects on BM progenitors, and during the first...

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Identifiers

PMID: 24825601
DOI: 10.1002/eji.201344350
PMCID: PMC4209805

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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