Article
Marginal zone B cells: virtues of innate-like antibody-producing lymphocytes.
Nature reviews. Immunology - 1 Feb 2013
Cerutti Andrea, Cols Montserrat, Puga Irene
Abstract excerpt
Protective responses to microorganisms involve the nonspecific but rapid defence mechanisms of the innate immune system, followed by the specific but slow defence mechanisms of the adaptive immune system. Located as sentinels at the interface between the circulation and lymphoid tissue, splenic marginal zone B cells rapidly respond to blood-borne antigens by adopting 'crossover' defensive strategies that blur the...
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