Article

B cells maintain the homeostasis of splenic marginal zone antigen-presenting cells to promote the anti-viral CD8 <sup>+</sup> T cell response

2025-05-01

Abstract excerpt

Natural killer and CD8 + T cells are critical in the elimination of blood-borne viruses such as cytomegalovirus (CMV); however, the role of B cells in this process is less clear. Here, using the murine CMV (MCMV) infection model, we demonstrated that the B cell-deficient mice mounted a weaker primary virus-specific CD8 + T cell response than their wild-type counterparts, which was associated with increased viral...

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Literature Corpus work: 7be476ef-0f52-5761-95d3-10db26c75ffc
DOI: 10.1101/2025.04.28.651045

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B cells maintain the homeostasis of splenic marginal zone antigen-presenting cells to promote the anti-viral CD8 <sup>+</sup> T cell responseDOI 10.1101/2025.04.28.651045Read

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