Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dosing strategy of tacrolimus when co-administered with Wuzhi tablet in renal transplant recipients.

International journal of clinical pharmacology and therapeutics - 1 Nov 2024

Dai Rui, Cai Yiting, Li Jun, Liu Xiaoman, Fu Qian, Huang Min, Wang Changxi, Chen Pan

Abstract excerpt

OBJECTIVE: Tacrolimus (TAC) is a first-line immunosuppressant to prevent allograft rejection. Wuzhi tablet is widely used as a TAC-sparing agent in China that could significantly elevate TAC exposure. However, insufficient data support the dose recommendation of TAC when co-administered with Wuzhi. MATERIALS AND METHODS: A total of 305 adult renal transplant patients with 2,541 TAC trough concentrations (C0) were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytochrome P-450 CYP3A
Share to Drugs, Chinese Herbal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunosuppressive Agents

Share to Kidney Transplantation

Share to Models, Biological

Share to Monte Carlo Method

Share to Pharmacogenomic Variants

Share to Tacrolimus

Source

Identifiers

PMID: 39157918
DOI: 10.5414/CP204561

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dosing strategy of tacrolimus when co-administered with Wuzhi tablet in renal transplant recipients.PMID 39157918Read ↗

Population pharmacokinetic analysis and dosing guidelines for tacrolimus co-administration with Wuzhi capsule in Chinese renal transplant recipients.Semantic proximity Read ↗

Prediction of tacrolimus and Wuzhi tablet pharmacokinetic interaction magnitude in renal transplant recipients.Semantic proximity Read ↗

Pharmacogenomics-based tacrolimus combined with Wuzhi capsules in precision medicine in kidney transplant patientsSemantic proximity Read ↗

Effect of drug combination on tacrolimus target dose in renal transplant patients with different CYP3A5 genotypes.Semantic proximity Read ↗

Effects and safety evaluation of Wuzhi Capsules combined with tacrolimus for the treatment of kidney transplantation recipients.Semantic proximity Read ↗

Population pharmacokinetics of tacrolimus in Chinese adult liver transplant patients.Semantic proximity Read ↗

Beneficial effects of Wuzhi Capsule on tacrolimus blood concentrations in liver transplant patients with different donor-recipient CYP3A5 genotypes.Semantic proximity Read ↗

Effect of Wuzhi preparations on tacrolimus in CYP3A5 expressers during the early period after transplantation: A real-life experience from heart transplant recipients.Semantic proximity Read ↗

Beneficial effects of traditional Chinese medicine Wuzhi Capsule on tacrolimus dose requirements in liver transplant patients with different donor-recipient CYP3A5 genotypesSemantic proximity Read ↗

Initial dosage optimization of tacrolimus in Chinese pediatric patients undergoing kidney transplantation based on population pharmacokinetics and pharmacogenetics.Semantic proximity Read ↗

Machine learning-based method for tacrolimus dose predictions in Chinese kidney transplant perioperative patients.Semantic proximity Read ↗

Optimization of initial dosing scheme of tacrolimus in pediatric refractory nephrotic syndrome patients based on CYP3A5 genotype and coadministration with wuzhi-capsuleSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.