Article

<i>Pituitary Tumor Transforming Gene 1</i> orchestrates gene regulatory variation in mouse ventral midbrain during aging

2020-05-16

Abstract excerpt

<h4>Background</h4> Dopaminergic neurons in the midbrain are of particular interest due to their role in diseases such as Parkinson’s disease and schizophrenia. Genetic variation between individuals can affect the integrity and function of dopaminergic neurons but the DNA variants and molecular cascades modulating dopaminergic neurons and other cells types of ventral midbrain remain poorly defined. Three genetica...

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Literature Corpus work: d2482236-e451-5207-b58c-0ac1b8aa2e63
DOI: 10.1101/2020.05.14.096156

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