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Article

Attenuation of epigenetic regulator SMARCA4 and ERK-ETS signaling suppresses aging-related dopaminergic degeneration

2019-11-12

Abstract excerpt

<h4>ABSTRACT</h4> Parkinson’s disease (PD) is a complex disease with high heterogeneity. How complex interactions of genetic, environmental factors and aging jointly contribute to dopaminergic degeneration in PD is largely unclear. Here, we applied frequent gene co-expression analysis on human patient substantia nigra-specific microarray datasets to identify potential novel disease-related genes. In vivo Drosoph...

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Literature Corpus work
e2e24962-0c5e-59d1-aa91-99f9e0717caa
DOI
10.1101/835876
Open publication

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Attenuation of epigenetic regulator SMARCA4 and ERK-ETS signaling suppresses aging-related dopaminergic degenerationDOI 10.1101/835876
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