Article

High-throughput selection of human <i>de novo</i> -emerged sORFs with high folding potential

2024-01-24

Abstract excerpt

De novo genes emerge from previously non-coding stretches of the genome. Their en-coded de novo proteins are generally expected to be similar to random sequences and, accordingly, with no stable tertiary fold and high predicted disorder. However, structural properties of de novo proteins and whether they differ during the stages of emergence and fixation have not been studied in depth and rely heavily on predict...

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Identifiers and source

Literature Corpus work: 2cd74a82-7613-57e1-9f4c-05e87132e462
DOI: 10.1101/2024.01.22.576604

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