Article

Angiotensin II type-1 receptor-associated protein interacts with transferrin receptor-1 and promotes its internalization

2022-07-19

Abstract excerpt

Kidney fibrosis is a common pathway that leads to chronic kidney disease. Angiotensin II type-1 receptor (AT1R)-associated protein (ATRAP) was originally identified as an AT1R-binding protein. Previously, we reported that systemic knockout of ATRAP exacerbates kidney fibrosis in aged mice. Although these effects of ATRAP appeared to be AT1R-independent actions, the molecular mechanism remains poorly understood. To...

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Literature Corpus work: 2ccf88d6-ae99-53eb-8b35-1faeb09fa05c
DOI: 10.21203/rs.3.rs-1830267/v1

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Angiotensin II type-1 receptor-associated protein interacts with transferrin receptor-1 and promotes its internalizationDOI 10.21203/rs.3.rs-1830267/v1Read

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