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Localization of angiotensin II type 1 receptor gene expression in rodent and human kidneys

22 Feb 2021

Abstract excerpt

Angiotensin II (ANG II) type 1 (AT1) receptors are essential for mediating the effects of ANG II in the kidneys. This study aimed to obtain a comprehensive overview about the cell-specific localization of AT1 receptor expression in rodent and human kidneys using the novel RNAscope technique. We found that the conserved AT1 receptor mRNA expression sites across species are the (juxta)glomerular areas and...

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PMID: 33615887
DOI: 10.1152/ajprenal.00550.2020

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