Article
Identification of Genes Related to the Early Stage of Angiotensin II-induced Acute Renal Injury by Microarray and Integrated Gene Network Analysis
1 Jan 2014
Abstract excerpt
BACKGROUND/AIMS: Angiotensin II (Ang II) mediated signaling plays a key role in the development of chronic kidney damage that contributes to renal fibrosis. However, the gene expression changes regulated by Ang II in the early stage of acute renal injury remain unclear. METHODS: C57BL/6 wild-type (WT) mice were injected with Ang II (1500 ng/kg/min) for 1, 3 and 7 days. A time series analysis of microarrays was...
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