Article
Expression of the iron transporter DMT1 in kidney from normal and anemic mk mice.
Kidney international - 1 Jul 2002
Canonne-Hergaux François, Gros Philippe
Abstract excerpt
BACKGROUND: DMT1 (Nramp2/DCT1) is the major apical iron transporter in absorptive cells of the duodenum, but also transports transferrin-iron across the membrane of acidified endosomes in peripheral tissues. DMT1 mRNA and protein expression has been detected in rat and mouse kidney, but its role at that site remains to be clarified. METHODS: Immunoblotting and immunohistochemistry with specific affinity purified...
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